Appetite

Procedures for assessing the effects of stimulants on appetite have
been developed for short-term, single dose experiments. Hoebel et
al. (1975) utilized a procedure that tests a drug's effectiveness in
reducing intake of a diet liquid meal product. Volunteers report to
the laboratory having refrained from eating for 2 hours prior to
lunchtime (12 noon). Using a double-blind cross-over design,
subjects were given either placebo or 25 mg of phenylpropanolamine
30 minutes before lunch. Lunch consisted of a canned chocolateflavored
drink which was dispensed via a long straw from a graduated
cylinder. The reservoir was hidden from the subject's view.
Subjects were instructed to drink as much as they wished.. Upon
completion of lunch they filled out questionnaires that related to
the taste of the lunch, the reason for stopping, the amount that
they consumed relative to the previous day, and the taste of the
lunch relative to the previous day.